Although it appears on many companies list of named reactions, most can only do it "with plant modifications". Pentagon are one of only a few companies with a purpose-built Grignard facility which was designed to excel at producing materials from this demanding chemistry.
Pentagon produce a range of reagents in standard concentrations in solvent systems including Tetrahydrofuran (THF), Methyl tertiary butyl ether (MTBE), Diethyl ether (DEE), Di-N-Butyl ether (DNBE) as well as Toluene/THF mixtures. A click on the link to the Grignard product range tells part of the story - however, we also have extensive experience in producing and reacting custom Grignards for third parties. Please contact us if there is an alternative product you would like to have manufactured for you.
The Grignard synthesis offers an extremely flexible route to the manufacture of a variety of final products.
Pentagon is able to produce a number of Grignard reagents in standard concentrations. As mentioned above, typical solvent systems include Diethyl ether, Di-n-butyl ether, Tetrahydrofuran and Methyl tertiary-butyl ether.
Generically the plant is capable of producing the following groups of Grignards:
- Alkyl Grignards
- Aryl Grignards
- Vinylic Grignards (development)
- Allylic Grignards
- Benzylic Grignards